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Marco Wachtel Selected Research

Aurora Kinase A

1/2020Aurora A Kinase Inhibition Destabilizes PAX3-FOXO1 and MYCN and Synergizes with Navitoclax to Induce Rhabdomyosarcoma Cell Death.

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Marco Wachtel Research Topics

Disease

31Neoplasms (Cancer)
03/2024 - 02/2006
12Alveolar Rhabdomyosarcoma
12/2023 - 08/2004
10Rhabdomyosarcoma
03/2024 - 08/2004
7Sarcoma (Soft Tissue Sarcoma)
03/2024 - 06/2010
7Ewing Sarcoma (Sarcoma, Ewing)
11/2023 - 11/2012
6Genetic Translocation (Chromosomal Translocation)
03/2024 - 07/2009
4Carcinogenesis
03/2024 - 08/2015
2Embryonal Rhabdomyosarcoma
01/2021 - 08/2004
2Leukemia
01/2018 - 08/2015
1Ataxia Telangiectasia (Louis Bar Syndrome)
12/2023
1Thyroid Neoplasms (Thyroid Cancer)
08/2015
1Melanoma (Melanoma, Malignant)
07/2009
1Breast Neoplasms (Breast Cancer)
07/2009
1Glioma (Gliomas)
07/2009
1Lymphoma (Lymphomas)
06/2009

Drug/Important Bio-Agent (IBA)

15Proteins (Proteins, Gene)FDA Link
03/2024 - 08/2004
8Transcription Factors (Transcription Factor)IBA
11/2023 - 05/2008
6ChromatinIBA
12/2023 - 01/2017
6EWS-FLI fusion proteinIBA
11/2023 - 01/2022
3Oncogene Proteins (Oncogene Protein)IBA
01/2022 - 01/2021
2Phosphotransferases (Kinase)IBA
03/2024 - 06/2010
2FenretinideIBA
01/2021 - 01/2020
2PAX3 Transcription FactorIBA
01/2015 - 05/2008
2Cadherins (E-Cadherin)IBA
06/2009 - 02/2006
1Vincristine (Oncovin)FDA LinkGeneric
03/2024
1Axl Receptor Tyrosine KinaseIBA
03/2024
1bemcentinibIBA
03/2024
1Cysteine (L-Cysteine)FDA Link
12/2023
1olaparibIBA
11/2023
1PlasticsIBA
10/2023
1Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
10/2023
1fimepinostatIBA
01/2022
1Monoclonal AntibodiesIBA
01/2021
1AntibodiesIBA
01/2021
1RNA (Ribonucleic Acid)IBA
05/2020
1Aurora Kinase AIBA
01/2020
1navitoclaxIBA
01/2020
1Dynamins (Dynamin)IBA
01/2020
1Mi-2 Nucleosome Remodeling and Deacetylase ComplexIBA
01/2020
1FurinIBA
11/2016
1Proprotein Convertases (Pro-Opiomelanocortin Converting Enzyme)IBA
11/2016
1BI 2536IBA
01/2015
1midostaurinIBA
11/2012
1Histone Deacetylases (Histone Deacetylase)IBA
06/2010
1tyrosine receptor (receptor, tyrosine)IBA
06/2010
1Proteasome Endopeptidase Complex (Proteasome)IBA
06/2010
1Cannabinoid Receptor AgonistsIBA
07/2009
1Dronabinol (THC)FDA LinkGeneric
07/2009
1HU 211 (HU 210)IBA
07/2009
1Cannabinoid Receptors (Cannabinoid Receptor)IBA
07/2009
1Fibrillin-2IBA
06/2009
1Biomarkers (Surrogate Marker)IBA
06/2009
1OligonucleotidesIBA
08/2004
1Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA
08/2004
1Pyridinolcarbamate (P23)IBA
08/2004

Therapy/Procedure

10Therapeutics
03/2024 - 05/2008
4Drug Therapy (Chemotherapy)
03/2024 - 01/2021
2Radiotherapy
01/2021 - 01/2021
1Aftercare (After-Treatment)
03/2024